Compared to linear peptides, cyclic peptides exhibit excellent biocompatibility and chemical diversity, making them effective in overcoming limitations and playing a crucial role in new…
View More Cyclic Peptide Synthesis Strategies in Drug Development
The formation of 2,5-diketopiperazine (DKP) with a bicyclic structure is one of the most detrimental side reactions and degradation pathways affecting peptide synthesis. Despite its crucial role as a…
View More Do Peptide Drugs Need Acylation Blocking at Nα?
Vaccines are considered one of the most successful medical interventions in the past few centuries, aiming to harness the human immune system and generate lasting…
View More Peptide Vaccine Design
Classes of Cell-Penetrating Peptides There are many types of cell-penetrating peptides (CPPs), and their classification is based on physicochemical properties, sources, intake mechanisms, and biomedical…
View More Classes and Applications of Cell-Penetrating Peptides
The FDA’s Center for Drug Evaluation and Research (CDER) regulatory approval of a total of 26 NME (New Molecular Entity) drugs in the first half…
View More FDA Approved Peptide Drugs in the First Half of 2023
What are cell penetrating peptides? Cell Penetrating Peptides (CPPs) are short peptides that have the ability to cross biological membranes and enter cells. They are able…
View More Cell Penetrating Peptides: Definition and Synthesis
Peptides are short chains of amino acids that have various biological activities and therapeutic potential. They play crucial roles in various biological processes, such as…
View More Microbial Fermentation — a Cost Effective Way to Obtain Peptides