Amino acids are carboxylic acids containing amino groups and are the building blocks of various proteins in living organisms. The amino acid molecule contains two…
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Author: alexbrowns
Medical Applications of Antimicrobial Peptides
Antimicrobial peptides mainly carry out non-specific rapid killing and intracellular interference on the cell membrane of harmful pathogens and do not target specific molecular pathways,…
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A Strategy for Site- and Chemoselective C-H Alkenylation through Osmaelectrooxidative Catalysis
Hydrocarbon activation has become a powerful tool in molecular science research and great progress has been made in molecular science research in recent years. In…
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Polymer Materials in Healthcare
Modern healthcare would not be possible without the usage of many polymer-based medical products. Many things we take for granted such as exam gloves, syringes,…
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Advances in siRNA Drug Research
siRNA, with a molecular weight of about 13 kDa, recruits the RNA-induced silencing complex (RISC) to mRNA through base pairing, thereby inhibiting protein translation…
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E. coli High Cell Density Fermentation Process
What is E. coli High Cell Density Fermentation? Among many expression systems, E. coli is the most commonly used prokaryotic expression system because of its…
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Several Types of Drug Conjugates
The clinical results and potential commercial value of drug conjugates, especially antibody drug conjugates (ADCs), have fueled the enthusiasm for M&A deals between companies and…
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How to Design A Good ADC Drug?
In the past ten years, the number of antibody-drug conjugates (ADCs) entering clinical trials has steadily increased. Currently, 9 ADCs have been approved, of which…
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Introduction of Isotope
Isotopes refer to different atoms of the same element, whose atoms have the same number of protons but different numbers of neutrons. The discovery of…
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Effects of Endocytosis on the Receptor Targeting Mechanism of ADC Drugs
ADC is a complex that conjugates cytotoxic small molecule drugs to monoclonal antibodies through a rationally constructed linker, which can selectively deliver effective cytotoxic drugs into…
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